• This is sweet

    From MarkE@me22over7@gmail.com to talk-origins on Thu Apr 16 16:25:04 2026
    From Newsgroup: talk.origins

    "One long-standing theory among chemists holds that ribose, a sugar that
    forms the structural backbone of RNA, arose spontaneously through a
    chemical process. However, new research challenges this idea."

    "In a study published in Chem, scientists from Scripps Research and the Georgia Institute of Technology question the validity of the rCLformose reactionrCY hypothesis. This hypothesis proposes that simple formaldehyde molecules reacted under early Earth conditions to form ribose. But the
    new findings reveal a key limitation: under controlled experimental conditions, the formose reaction does not yield linear sugars like
    ribose. Instead, it predominantly produces branched sugar structures,
    which are incompatible with the formation of RNA."

    "Since almost all of the sugars that are used as molecular building
    blocks in living organisms are linear and unbranched, this suggests that
    the formose reaction cannot explain the origins of biotic sugars."

    "rCLThe concept of the formose reaction as a prebiotic source of ribose
    needs serious reconsideration,rCY says corresponding author Ramanarayanan Krishnamurthy, professor of chemistry at Scripps Research."

    The problem is, unbranched sugars are are needed on a prebiotic earth
    and difficult to synthesise.

    rCLOur goal was to point out all the problems that you will face if you
    are thinking about the formose reaction in the context of the prebiotic
    sugar synthesis, but we arenrCOt saying this is the endpoint; our results might inspire somebody to come up with a better way to somehow overcome
    these issues,rCY says Krishnamurthy. rCLWe encourage the community to think differently and search for alternative solutions to explain how sugar molecules arose on early Earth.rCY

    https://scitechdaily.com/new-research-challenges-160-year-old-long-standing-origin-of-life-theory/#:~:text=%E2%80%9COur%20work%20might%20be%20helpful,%2C%2023%20April%202025%2C%20Chem.&text=j.chempr.2025.102553-,What%20is%20this?,Grant%2020%2DEXO%2D0006.

    Alternatives to the formose reaction have been proposed (e.g. https://pubs.acs.org/doi/10.1021/acsearthspacechem.5c00097), but this
    case is another data point in a trend I've been predicting: OoL stalling
    as reality bites - prebiotic chemistry constraints and protocell
    complexity.

    _______

    "Whoa-hoh-oh, the gaps are gettin' bigger
    Yeah-eah, mmm they're gettin' bigger"

    --- Synchronet 3.21f-Linux NewsLink 1.2
  • From RonO@rokimoto557@gmail.com to talk-origins on Thu Apr 16 09:23:40 2026
    From Newsgroup: talk.origins

    On 4/16/2026 1:25 AM, MarkE wrote:
    "One long-standing theory among chemists holds that ribose, a sugar that forms the structural backbone of RNA, arose spontaneously through a
    chemical process. However, new research challenges this idea."

    "In a study published in Chem, scientists from Scripps Research and the Georgia Institute of Technology question the validity of the rCLformose reactionrCY hypothesis. This hypothesis proposes that simple formaldehyde molecules reacted under early Earth conditions to form ribose. But the
    new findings reveal a key limitation: under controlled experimental conditions, the formose reaction does not yield linear sugars like
    ribose. Instead, it predominantly produces branched sugar structures,
    which are incompatible with the formation of RNA."

    "Since almost all of the sugars that are used as molecular building
    blocks in living organisms are linear and unbranched, this suggests that
    the formose reaction cannot explain the origins of biotic sugars."

    "rCLThe concept of the formose reaction as a prebiotic source of ribose needs serious reconsideration,rCY says corresponding author Ramanarayanan Krishnamurthy, professor of chemistry at Scripps Research."

    The problem is, unbranched sugars are are needed on a prebiotic earth
    and difficult to synthesise.

    rCLOur goal was to point out all the problems that you will face if you
    are thinking about the formose reaction in the context of the prebiotic sugar synthesis, but we arenrCOt saying this is the endpoint; our results might inspire somebody to come up with a better way to somehow overcome these issues,rCY says Krishnamurthy. rCLWe encourage the community to think differently and search for alternative solutions to explain how sugar molecules arose on early Earth.rCY

    https://scitechdaily.com/new-research-challenges-160-year-old-long- standing-origin-of-life-theory/ #:~:text=%E2%80%9COur%20work%20might%20be%20helpful, %2C%2023%20April%202025%2C%20Chem.&text=j.chempr.2025.102553-,What%20is%20this?,Grant%2020%2DEXO%2D0006.

    Alternatives to the formose reaction have been proposed (e.g. https:// pubs.acs.org/doi/10.1021/acsearthspacechem.5c00097), but this case is another data point in a trend I've been predicting: OoL stalling as
    reality bites - prebiotic chemistry constraints and protocell complexity.

    _______

    "Whoa-hoh-oh, the gaps are gettin' bigger
    -aYeah-eah, mmm they're gettin' bigger"


    Gee whiz bumble bees can't fly. You should know that ribose has been
    found on asteroids like Bennu. Bennu has evidence that it once had some liquid water inside of it, but it has been out in space, orbiting the
    sun, for a very long time. How did ribose get made on an asteroid under likely less than optimal conditions? Bennu also had all the nucleobases
    of DNA and RNA.

    You are likely experiencing a nervous breakdown with your inability to
    deal rationally with reality. You likely need to take some time to put yourself back together. Torturing yourself by putting up this junk
    isn't going to help you.

    Ron Okimoto

    --- Synchronet 3.21f-Linux NewsLink 1.2
  • From MarkE@me22over7@gmail.com to talk-origins on Fri Apr 17 09:09:53 2026
    From Newsgroup: talk.origins

    On 17/04/2026 12:23 am, RonO wrote:
    On 4/16/2026 1:25 AM, MarkE wrote:
    "One long-standing theory among chemists holds that ribose, a sugar
    that forms the structural backbone of RNA, arose spontaneously through
    a chemical process. However, new research challenges this idea."

    "In a study published in Chem, scientists from Scripps Research and
    the Georgia Institute of Technology question the validity of the
    rCLformose reactionrCY hypothesis. This hypothesis proposes that simple
    formaldehyde molecules reacted under early Earth conditions to form
    ribose. But the new findings reveal a key limitation: under controlled
    experimental conditions, the formose reaction does not yield linear
    sugars like ribose. Instead, it predominantly produces branched sugar
    structures, which are incompatible with the formation of RNA."

    "Since almost all of the sugars that are used as molecular building
    blocks in living organisms are linear and unbranched, this suggests
    that the formose reaction cannot explain the origins of biotic sugars."

    "rCLThe concept of the formose reaction as a prebiotic source of ribose
    needs serious reconsideration,rCY says corresponding author
    Ramanarayanan Krishnamurthy, professor of chemistry at Scripps Research."

    The problem is, unbranched sugars are are needed on a prebiotic earth
    and difficult to synthesise.

    rCLOur goal was to point out all the problems that you will face if you
    are thinking about the formose reaction in the context of the
    prebiotic sugar synthesis, but we arenrCOt saying this is the endpoint;
    our results might inspire somebody to come up with a better way to
    somehow overcome these issues,rCY says Krishnamurthy. rCLWe encourage the >> community to think differently and search for alternative solutions to
    explain how sugar molecules arose on early Earth.rCY

    https://scitechdaily.com/new-research-challenges-160-year-old-long-
    standing-origin-of-life-theory/
    #:~:text=%E2%80%9COur%20work%20might%20be%20helpful,
    %2C%2023%20April%202025%2C%20Chem.&text=j.chempr.2025.102553-,What%20is%20this?,Grant%2020%2DEXO%2D0006.

    Alternatives to the formose reaction have been proposed (e.g. https://
    pubs.acs.org/doi/10.1021/acsearthspacechem.5c00097), but this case is
    another data point in a trend I've been predicting: OoL stalling as
    reality bites - prebiotic chemistry constraints and protocell complexity.

    _______

    "Whoa-hoh-oh, the gaps are gettin' bigger
    -a-aYeah-eah, mmm they're gettin' bigger"


    Gee whiz bumble bees can't fly.-a You should know that ribose has been
    found on asteroids like Bennu.-a Bennu has evidence that it once had some liquid water inside of it, but it has been out in space, orbiting the
    sun, for a very long time.-a How did ribose get made on an asteroid under likely less than optimal conditions?-a Bennu also had all the nucleobases
    of DNA and RNA.

    You are likely experiencing a nervous breakdown with your inability to
    deal rationally with reality.-a You likely need to take some time to put yourself back together.-a Torturing yourself by putting up this junk
    isn't going to help you.

    Ron Okimoto


    Your denial shows your dishonesty and bait and switch. You must stop
    lying to yourself and stop trying to scam the other rubes, perps and
    idiots. I've told you to stop denying reality and explained the truth to
    you but at best you have been a wilfully ignorant and incompetent rube,
    but you are likely closer to being as bogus and dishonest as the perps.
    Can you not deal with reality in any sane manner? You need to reconcile
    your beliefs with reality. There is absolutely no reason for you to
    continue to lie to yourself about the scam just to support beliefs that
    you know are not consistent with reality. You have been wrong and
    dishonest because of wilful ignorance and lying to yourself about the
    issue. You are dishonest enough to keep pursuing the denial even though
    it would demonstrate that your beliefs are wrong. I've told you to stop
    being a perp, rube, idiot, scam artist. Can you not deal with reality in
    any sane manner? Your denial shows your dishonesty and bait and switch.
    You must stop lying to yourself and stop trying to scam the other rubes,
    perps and idiots. I've told you to stop denying reality and explained
    the truth to you but at best you have been a wilfully ignorant and
    incompetent rube, but you are likely closer to being as bogus and
    dishonest as the perps. Can you not deal with reality in any sane
    manner? You need to reconcile your beliefs with reality. There is
    absolutely no reason for you to continue to lie to yourself about the
    scam just to support beliefs that you know are not consistent with
    reality. You have been wrong and dishonest because of wilful ignorance
    and lying to yourself about the issue. You are dishonest enough to keep pursuing the denial even though it would demonstrate that your beliefs
    are wrong. I've told you to stop being a perp, rube, idiot, scam artist.
    Can you not deal with reality in any sane manner? Your denial shows your dishonesty and bait and switch. You must stop lying to yourself and stop trying to scam the other rubes, perps and idiots. I've told you to stop denying reality and explained the truth to you but at best you have been
    a wilfully ignorant and incompetent rube, but you are likely closer to
    being as bogus and dishonest as the perps. Can you not deal with reality
    in any sane manner? You need to reconcile your beliefs with reality.
    There is absolutely no reason for you to continue to lie to yourself
    about the scam just to support beliefs that you know are not consistent
    with reality. You have been wrong and dishonest because of wilful
    ignorance and lying to yourself about the issue. You are dishonest
    enough to keep pursuing the denial even though it would demonstrate that
    your beliefs are wrong. I've told you to stop being a perp, rube, idiot,
    scam artist. Can you not deal with reality in any sane manner? Your
    denial shows your dishonesty and bait and switch. You must stop lying to yourself and stop trying to scam the other rubes, perps and idiots. I've
    told you to stop denying reality and explained the truth to you but at
    best you have been a wilfully ignorant and incompetent rube, but you are likely closer to being as bogus and dishonest as the perps. Can you not
    deal with reality in any sane manner? You need to reconcile your beliefs
    with reality. There is absolutely no reason for you to continue to lie
    to yourself about the scam just to support beliefs that you know are not consistent with reality. You have been wrong and dishonest because of
    wilful ignorance and lying to yourself about the issue. You are
    dishonest enough to keep pursuing the denial even though it would
    demonstrate that your beliefs are wrong. I've told you to stop being a
    perp, rube, idiot, scam artist. Can you not deal with reality in any
    sane manner? Your denial shows your dishonesty and bait and switch. You
    must stop lying to yourself and stop trying to scam the other rubes,
    perps and idiots. I've told you to stop denying reality and explained
    the truth to you but at best you have been a wilfully ignorant and
    incompetent rube, but you are likely closer to being as bogus and
    dishonest as the perps. Can you not deal with reality in any sane
    manner? You need to reconcile your beliefs with reality. There is
    absolutely no reason for you to continue to lie to yourself about the
    scam just to support beliefs that you know are not consistent with
    reality. You have been wrong and dishonest because of wilful ignorance
    and lying to yourself about the issue. You are dishonest enough to keep pursuing the denial even though it would demonstrate that your beliefs
    are wrong. I've told you to stop being a perp, rube, idiot, scam artist.
    Can you not deal with reality in any sane manner?

    --- Synchronet 3.21f-Linux NewsLink 1.2
  • From ShyDavid@noreply@murdermingle.com to talk-origins on Thu Apr 16 17:58:35 2026
    From Newsgroup: talk.origins

    On 2026/04/16 5:09 PM, MarkE wrote:
    On 17/04/2026 12:23 am, RonO wrote:
    On 4/16/2026 1:25 AM, MarkE wrote:
    "One long-standing theory among chemists holds that ribose, a sugar that forms the structural backbone of RNA, arose spontaneously through a chemical process. However, new research challenges this idea."

    "In a study published in Chem, scientists from Scripps Research and the Georgia Institute of Technology question the validity of the rCLformose reactionrCY hypothesis. This hypothesis proposes that simple formaldehyde molecules reacted under early Earth conditions to form ribose. But the new findings reveal a key limitation: under controlled experimental conditions, the formose reaction does not yield linear sugars like ribose. Instead, it predominantly produces branched sugar structures, which are incompatible with the formation of RNA."

    "Since almost all of the sugars that are used as molecular building blocks in living organisms are linear and unbranched, this suggests that the formose reaction cannot explain the origins of biotic sugars."

    "rCLThe concept of the formose reaction as a prebiotic source of ribose needs serious reconsideration,rCY says corresponding author Ramanarayanan Krishnamurthy, professor of chemistry at Scripps Research."

    The problem is, unbranched sugars are are needed on a prebiotic earth and difficult to synthesise.

    rCLOur goal was to point out all the problems that you will face if you are thinking about the formose reaction in the context of the prebiotic sugar synthesis, but we arenrCOt saying this is the endpoint; our results might inspire somebody to come up with a better way to somehow overcome these issues,rCY says Krishnamurthy. rCLWe encourage the community to think differently and search for alternative solutions to explain how sugar molecules arose on early Earth.rCY

    https://scitechdaily.com/new-research-challenges-160-year-old-long- standing-origin-of-life-theory/ #:~:text=%E2%80%9COur%20work%20might%20be%20helpful, %2C%2023%20April%202025%2C%20Chem.&text=j.chempr.2025.102553-,What%20is%20this?,Grant%2020%2DEXO%2D0006.

    Alternatives to the formose reaction have been proposed (e.g. https:// pubs.acs.org/doi/10.1021/acsearthspacechem.5c00097), but this case is another data point in a trend I've been predicting: OoL stalling as reality bites - prebiotic chemistry constraints and protocell complexity.

    _______

    "Whoa-hoh-oh, the gaps are gettin' bigger
    -a-aYeah-eah, mmm they're gettin' bigger"


    Gee whiz bumble bees can't fly.-a You should know that ribose has been found on asteroids like Bennu.-a Bennu has evidence that it once had some liquid water inside of it, but it has been out in space, orbiting the sun, for a very long time.-a How did ribose get made on an asteroid under likely less than optimal conditions?-a Bennu also had all the nucleobases of DNA and RNA.

    You are likely experiencing a nervous breakdown with your inability to deal rationally with reality.-a You likely need to take some time to put yourself back together.-a Torturing yourself by putting up this junk isn't going to help you.

    Ron Okimoto


    Your denial shows your dishonesty and bait and switch. You must stop lying to yourself and stop trying to scam the other rubes, perps and idiots. I've told you to stop denying reality and explained the truth to you but at best you have been a wilfully ignorant and incompetent rube, but you are likely closer to being as bogus and dishonest as the perps. Can you not deal with reality in any sane manner? You need to reconcile your beliefs with reality. There is absolutely no reason for you to continue to lie to yourself about the scam just to support beliefs that you know are not consistent with reality. You have been wrong and dishonest because of wilful ignorance and lying to yourself about the issue. You are dishonest enough to keep pursuing the denial even though it would demonstrate that your beliefs are wrong. I've told you to stop being a perp, rube, idiot, scam artist. Can you not deal with reality in any sane manner? Your denial shows your dishonesty and bait and
    switch. You must stop lying to yourself and stop trying to scam the other rubes, perps and idiots. I've told you to stop denying reality and explained the truth to you but at best you have been a wilfully ignorant and incompetent rube, but you are likely closer to being as bogus and dishonest as the perps. Can you not deal with reality in any sane manner? You need to reconcile your beliefs with reality. There is absolutely no reason for you to continue to lie to yourself about the scam just to support beliefs that you know are not consistent with reality. You have been wrong and dishonest because of wilful ignorance and lying to yourself about the issue. You are dishonest enough to keep pursuing the denial even though it would demonstrate that your beliefs are wrong. I've told you to stop being a perp, rube, idiot, scam artist. Can you not deal with reality in any sane manner? Your denial shows your dishonesty and bait and switch. You must stop lying to yourself and stop
    trying to scam the other rubes, perps and idiots. I've told you to stop denying reality and explained the truth to you but at best you have been a wilfully ignorant and incompetent rube, but you are likely closer to being as bogus and dishonest as the perps. Can you not deal with reality in any sane manner? You need to reconcile your beliefs with reality. There is absolutely no reason for you to continue to lie to yourself about the scam just to support beliefs that you know are not consistent with reality. You have been wrong and dishonest because of wilful ignorance and lying to yourself about the issue. You are dishonest enough to keep pursuing the denial even though it would demonstrate that your beliefs are wrong. I've told you to stop being a perp, rube, idiot, scam artist. Can you not deal with reality in any sane manner? Your denial shows your dishonesty and bait and switch. You must stop lying to yourself and stop trying to scam the other rubes, perps and idiots.
    I've told you to stop denying reality and explained the truth to you but at best you have been a wilfully ignorant and incompetent rube, but you are likely closer to being as bogus and dishonest as the perps. Can you not deal with reality in any sane manner? You need to reconcile your beliefs with reality. There is absolutely no reason for you to continue to lie to yourself about the scam just to support beliefs that you know are not consistent with reality. You have been wrong and dishonest because of wilful ignorance and lying to yourself about the issue. You are dishonest enough to keep pursuing the denial even though it would demonstrate that your beliefs are wrong. I've told you to stop being a perp, rube, idiot, scam artist. Can you not deal with reality in any sane manner? Your denial shows your dishonesty and bait and switch. You must stop lying to yourself and stop trying to scam the other rubes, perps and idiots. I've told you to stop denying reality and explained
    the truth to you but at best you have been a wilfully ignorant and incompetent rube, but you are likely closer to being as bogus and dishonest as the perps. Can you not deal with reality in any sane manner? You need to reconcile your beliefs with reality. There is absolutely no reason for you to continue to lie to yourself about the scam just to support beliefs that you know are not consistent with reality. You have been wrong and dishonest because of wilful ignorance and lying to yourself about the issue. You are dishonest enough to keep pursuing the denial even though it would demonstrate that your beliefs are wrong. I've told you to stop being a perp, rube, idiot, scam artist. Can you not deal with reality in any sane manner?


    One long, tedious gaslighting. Way cool! talk.origins hasn't changed in 30+ years.
    --
    ShyDavid


    --- Synchronet 3.21f-Linux NewsLink 1.2
  • From sticks@wolverine01@charter.net to talk-origins on Thu Apr 16 19:22:29 2026
    From Newsgroup: talk.origins

    On 4/16/2026 6:58 PM, ShyDavid wrote:
    On 2026/04/16 5:09 PM, MarkE wrote:

    Your denial shows your dishonesty and bait and switch. You must stop
    lying to yourself and stop trying to scam the other rubes, perps and
    idiots. I've told you to stop denying reality and explained the truth
    to you but at best you have been a wilfully ignorant and incompetent
    rube, but you are likely closer to being as bogus and dishonest as the
    perps. Can you not deal with reality in any sane manner? You need to
    reconcile your beliefs with reality. There is absolutely no reason for
    you to continue to lie to yourself about the scam just to support
    beliefs that you know are not consistent with reality. You have been
    wrong and dishonest because of wilful ignorance and lying to yourself
    about the issue. You are dishonest enough to keep pursuing the denial
    even though it would demonstrate that your beliefs are wrong. I've
    told you to stop being a perp, rube, idiot, scam artist. Can you not
    deal with reality in any sane manner? Your denial shows your
    dishonesty and bait and switch. You must stop lying to yourself and
    stop trying to scam the other rubes, perps and idiots. I've told you
    to stop denying reality and explained the truth to you but at best you
    have been a wilfully ignorant and incompetent rube, but you are likely
    closer to being as bogus and dishonest as the perps. Can you not deal
    with reality in any sane manner? You need to reconcile your beliefs
    with reality. There is absolutely no reason for you to continue to lie
    to yourself about the scam just to support beliefs that you know are
    not consistent with reality. You have been wrong and dishonest because
    of wilful ignorance and lying to yourself about the issue. You are
    dishonest enough to keep pursuing the denial even though it would
    demonstrate that your beliefs are wrong. I've told you to stop being a
    perp, rube, idiot, scam artist. Can you not deal with reality in any
    sane manner? Your denial shows your dishonesty and bait and switch.
    You must stop lying to yourself and stop trying to scam the other
    rubes, perps and idiots. I've told you to stop denying reality and
    explained the truth to you but at best you have been a wilfully
    ignorant and incompetent rube, but you are likely closer to being as
    bogus and dishonest as the perps. Can you not deal with reality in any
    sane manner? You need to reconcile your beliefs with reality. There is
    absolutely no reason for you to continue to lie to yourself about the
    scam just to support beliefs that you know are not consistent with
    reality. You have been wrong and dishonest because of wilful ignorance
    and lying to yourself about the issue. You are dishonest enough to
    keep pursuing the denial even though it would demonstrate that your
    beliefs are wrong. I've told you to stop being a perp, rube, idiot,
    scam artist. Can you not deal with reality in any sane manner? Your
    denial shows your dishonesty and bait and switch. You must stop lying
    to yourself and stop trying to scam the other rubes, perps and idiots.
    I've told you to stop denying reality and explained the truth to you
    but at best you have been a wilfully ignorant and incompetent rube,
    but you are likely closer to being as bogus and dishonest as the
    perps. Can you not deal with reality in any sane manner? You need to
    reconcile your beliefs with reality. There is absolutely no reason for
    you to continue to lie to yourself about the scam just to support
    beliefs that you know are not consistent with reality. You have been
    wrong and dishonest because of wilful ignorance and lying to yourself
    about the issue. You are dishonest enough to keep pursuing the denial
    even though it would demonstrate that your beliefs are wrong. I've
    told you to stop being a perp, rube, idiot, scam artist. Can you not
    deal with reality in any sane manner? Your denial shows your
    dishonesty and bait and switch. You must stop lying to yourself and
    stop trying to scam the other rubes, perps and idiots. I've told you
    to stop denying reality and explained the truth to you but at best you
    have been a wilfully ignorant and incompetent rube, but you are likely
    closer to being as bogus and dishonest as the perps. Can you not deal
    with reality in any sane manner? You need to reconcile your beliefs
    with reality. There is absolutely no reason for you to continue to lie
    to yourself about the scam just to support beliefs that you know are
    not consistent with reality. You have been wrong and dishonest because
    of wilful ignorance and lying to yourself about the issue. You are
    dishonest enough to keep pursuing the denial even though it would
    demonstrate that your beliefs are wrong. I've told you to stop being a
    perp, rube, idiot, scam artist. Can you not deal with reality in any
    sane manner?


    One long, tedious gaslighting. Way cool! talk.origins hasn't changed in
    30+ years.

    <whoosh>
    --
    Science DoesnrCOt Support Darwin. Scientists Do

    --- Synchronet 3.21f-Linux NewsLink 1.2
  • From RonO@rokimoto557@gmail.com to talk-origins on Fri Apr 17 10:30:56 2026
    From Newsgroup: talk.origins

    On 4/16/2026 6:09 PM, MarkE wrote:
    On 17/04/2026 12:23 am, RonO wrote:
    On 4/16/2026 1:25 AM, MarkE wrote:
    "One long-standing theory among chemists holds that ribose, a sugar
    that forms the structural backbone of RNA, arose spontaneously
    through a chemical process. However, new research challenges this idea." >>>
    "In a study published in Chem, scientists from Scripps Research and
    the Georgia Institute of Technology question the validity of the
    rCLformose reactionrCY hypothesis. This hypothesis proposes that simple >>> formaldehyde molecules reacted under early Earth conditions to form
    ribose. But the new findings reveal a key limitation: under
    controlled experimental conditions, the formose reaction does not
    yield linear sugars like ribose. Instead, it predominantly produces
    branched sugar structures, which are incompatible with the formation
    of RNA."

    "Since almost all of the sugars that are used as molecular building
    blocks in living organisms are linear and unbranched, this suggests
    that the formose reaction cannot explain the origins of biotic sugars."

    "rCLThe concept of the formose reaction as a prebiotic source of ribose >>> needs serious reconsideration,rCY says corresponding author
    Ramanarayanan Krishnamurthy, professor of chemistry at Scripps
    Research."

    The problem is, unbranched sugars are are needed on a prebiotic earth
    and difficult to synthesise.

    rCLOur goal was to point out all the problems that you will face if you >>> are thinking about the formose reaction in the context of the
    prebiotic sugar synthesis, but we arenrCOt saying this is the endpoint; >>> our results might inspire somebody to come up with a better way to
    somehow overcome these issues,rCY says Krishnamurthy. rCLWe encourage the >>> community to think differently and search for alternative solutions
    to explain how sugar molecules arose on early Earth.rCY

    https://scitechdaily.com/new-research-challenges-160-year-old-long-
    standing-origin-of-life-theory/
    #:~:text=%E2%80%9COur%20work%20might%20be%20helpful,
    %2C%2023%20April%202025%2C%20Chem.&text=j.chempr.2025.102553-,What%20is%20this?,Grant%2020%2DEXO%2D0006.

    Alternatives to the formose reaction have been proposed (e.g.
    https:// pubs.acs.org/doi/10.1021/acsearthspacechem.5c00097), but
    this case is another data point in a trend I've been predicting: OoL
    stalling as reality bites - prebiotic chemistry constraints and
    protocell complexity.

    _______

    "Whoa-hoh-oh, the gaps are gettin' bigger
    -a-aYeah-eah, mmm they're gettin' bigger"


    Gee whiz bumble bees can't fly.-a You should know that ribose has been
    found on asteroids like Bennu.-a Bennu has evidence that it once had
    some liquid water inside of it, but it has been out in space, orbiting
    the sun, for a very long time.-a How did ribose get made on an asteroid
    under likely less than optimal conditions?-a Bennu also had all the
    nucleobases of DNA and RNA.

    You are likely experiencing a nervous breakdown with your inability to
    deal rationally with reality.-a You likely need to take some time to
    put yourself back together.-a Torturing yourself by putting up this
    junk isn't going to help you.

    Ron Okimoto


    Your denial shows your dishonesty and bait and switch. You must stop
    lying to yourself and stop trying to scam the other rubes, perps and
    idiots. I've told you to stop denying reality and explained the truth to
    you but at best you have been a wilfully ignorant and incompetent rube,
    but you are likely closer to being as bogus and dishonest as the perps.
    Can you not deal with reality in any sane manner? You need to reconcile
    your beliefs with reality. There is absolutely no reason for you to
    continue to lie to yourself about the scam just to support beliefs that
    you know are not consistent with reality. You have been wrong and
    dishonest because of wilful ignorance and lying to yourself about the
    issue. You are dishonest enough to keep pursuing the denial even though
    it would demonstrate that your beliefs are wrong. I've told you to stop being a perp, rube, idiot, scam artist. Can you not deal with reality in
    any sane manner? Your denial shows your dishonesty and bait and switch.
    You must stop lying to yourself and stop trying to scam the other rubes, perps and idiots. I've told you to stop denying reality and explained
    the truth to you but at best you have been a wilfully ignorant and incompetent rube, but you are likely closer to being as bogus and
    dishonest as the perps. Can you not deal with reality in any sane
    manner? You need to reconcile your beliefs with reality. There is
    absolutely no reason for you to continue to lie to yourself about the
    scam just to support beliefs that you know are not consistent with
    reality. You have been wrong and dishonest because of wilful ignorance
    and lying to yourself about the issue. You are dishonest enough to keep pursuing the denial even though it would demonstrate that your beliefs
    are wrong. I've told you to stop being a perp, rube, idiot, scam artist.
    Can you not deal with reality in any sane manner? Your denial shows your dishonesty and bait and switch. You must stop lying to yourself and stop trying to scam the other rubes, perps and idiots. I've told you to stop denying reality and explained the truth to you but at best you have been
    a wilfully ignorant and incompetent rube, but you are likely closer to
    being as bogus and dishonest as the perps. Can you not deal with reality
    in any sane manner? You need to reconcile your beliefs with reality.
    There is absolutely no reason for you to continue to lie to yourself
    about the scam just to support beliefs that you know are not consistent
    with reality. You have been wrong and dishonest because of wilful
    ignorance and lying to yourself about the issue. You are dishonest
    enough to keep pursuing the denial even though it would demonstrate that your beliefs are wrong. I've told you to stop being a perp, rube, idiot, scam artist. Can you not deal with reality in any sane manner? Your
    denial shows your dishonesty and bait and switch. You must stop lying to yourself and stop trying to scam the other rubes, perps and idiots. I've told you to stop denying reality and explained the truth to you but at
    best you have been a wilfully ignorant and incompetent rube, but you are likely closer to being as bogus and dishonest as the perps. Can you not
    deal with reality in any sane manner? You need to reconcile your beliefs with reality. There is absolutely no reason for you to continue to lie
    to yourself about the scam just to support beliefs that you know are not consistent with reality. You have been wrong and dishonest because of
    wilful ignorance and lying to yourself about the issue. You are
    dishonest enough to keep pursuing the denial even though it would demonstrate that your beliefs are wrong. I've told you to stop being a
    perp, rube, idiot, scam artist. Can you not deal with reality in any
    sane manner? Your denial shows your dishonesty and bait and switch. You
    must stop lying to yourself and stop trying to scam the other rubes,
    perps and idiots. I've told you to stop denying reality and explained
    the truth to you but at best you have been a wilfully ignorant and incompetent rube, but you are likely closer to being as bogus and
    dishonest as the perps. Can you not deal with reality in any sane
    manner? You need to reconcile your beliefs with reality. There is
    absolutely no reason for you to continue to lie to yourself about the
    scam just to support beliefs that you know are not consistent with
    reality. You have been wrong and dishonest because of wilful ignorance
    and lying to yourself about the issue. You are dishonest enough to keep pursuing the denial even though it would demonstrate that your beliefs
    are wrong. I've told you to stop being a perp, rube, idiot, scam artist.
    Can you not deal with reality in any sane manner?

    You need to take a break and deal with your deteriorating mental
    condition. There is no reason to keep lying to yourself about reality.
    You know that you determined for yourself that your denial was senseless
    and stupid, and your reliance on scam artists was just stupid and
    dishonest. You should realize by now how you were fooled by Meyer. You
    need to deal with the fact that all you ever wanted from the ID perps
    was to be lied to. You need to be lied to. That is no way to exist,
    and no way to support your religious beliefs.

    Ron Okimoto

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  • From ShyDavid@noreply@murdermingle.com to talk-origins on Fri Apr 17 10:26:17 2026
    From Newsgroup: talk.origins

    On 2026/04/16 6:22 PM, sticks wrote:
    On 4/16/2026 6:58 PM, ShyDavid wrote:
    On 2026/04/16 5:09 PM, MarkE wrote:

    Your denial shows your dishonesty and bait and switch. You must stop lying to yourself and stop trying to scam the other rubes, perps and idiots. I've told you to stop denying reality and explained the truth to you but at best you have been a wilfully ignorant and incompetent rube, but you are likely closer to being as bogus and dishonest as the perps. Can you not deal with reality in any sane manner? You need to reconcile your beliefs with reality. There is absolutely no reason for you to continue to lie to yourself about the scam just to support beliefs that you know are not consistent with reality. You have been wrong and dishonest because of wilful ignorance and lying to yourself about the issue. You are dishonest enough to keep pursuing the denial even though it would demonstrate that your beliefs are wrong. I've told you to stop being a perp, rube, idiot, scam artist. Can you not deal with reality in any sane manner? Your denial shows your dishonesty and bait and
    switch. You must stop lying to yourself and stop trying to scam the other rubes, perps and idiots. I've told you to stop denying reality and explained the truth to you but at best you have been a wilfully ignorant and incompetent rube, but you are likely closer to being as bogus and dishonest as the perps. Can you not deal with reality in any sane manner? You need to reconcile your beliefs with reality. There is absolutely no reason for you to continue to lie to yourself about the scam just to support beliefs that you know are not consistent with reality. You have been wrong and dishonest because of wilful ignorance and lying to yourself about the issue. You are dishonest enough to keep pursuing the denial even though it would demonstrate that your beliefs are wrong. I've told you to stop being a perp, rube, idiot, scam artist. Can you not deal with reality in any sane manner? Your denial shows your dishonesty and bait and switch. You must stop lying to yourself and stop
    trying to scam the other rubes, perps and idiots. I've told you to stop denying reality and explained the truth to you but at best you have been a wilfully ignorant and incompetent rube, but you are likely closer to being as bogus and dishonest as the perps. Can you not deal with reality in any sane manner? You need to reconcile your beliefs with reality. There is absolutely no reason for you to continue to lie to yourself about the scam just to support beliefs that you know are not consistent with reality. You have been wrong and dishonest because of wilful ignorance and lying to yourself about the issue. You are dishonest enough to keep pursuing the denial even though it would demonstrate that your beliefs are wrong. I've told you to stop being a perp, rube, idiot, scam artist. Can you not deal with reality in any sane manner? Your denial shows your dishonesty and bait and switch. You must stop lying to yourself and stop trying to scam the other rubes, perps and idiots.
    I've told you to stop denying reality and explained the truth to you but at best you have been a wilfully ignorant and incompetent rube, but you are likely closer to being as bogus and dishonest as the perps. Can you not deal with reality in any sane manner? You need to reconcile your beliefs with reality. There is absolutely no reason for you to continue to lie to yourself about the scam just to support beliefs that you know are not consistent with reality. You have been wrong and dishonest because of wilful ignorance and lying to yourself about the issue. You are dishonest enough to keep pursuing the denial even though it would demonstrate that your beliefs are wrong. I've told you to stop being a perp, rube, idiot, scam artist. Can you not deal with reality in any sane manner? Your denial shows your dishonesty and bait and switch. You must stop lying to yourself and stop trying to scam the other rubes, perps and idiots. I've told you to stop denying reality and
    explained the truth to you but at best you have been a wilfully ignorant and incompetent rube, but you are likely closer to being as bogus and dishonest as the perps. Can you not deal with reality in any sane manner? You need to reconcile your beliefs with reality. There is absolutely no reason for you to continue to lie to yourself about the scam just to support beliefs that you know are not consistent with reality. You have been wrong and dishonest because of wilful ignorance and lying to yourself about the issue. You are dishonest enough to keep pursuing the denial even though it would demonstrate that your beliefs are wrong. I've told you to stop being a perp, rube, idiot, scam artist. Can you not deal with reality in any sane manner?
    '

    One long, tedious gaslighting. Way cool! talk.origins hasn't changed in 30+ years.

    <whoosh>

    Yep. Next the genius will be insisting "It's still Obama's fault."
    --
    ShyDavid

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