THE COSMOLOGICAL MODEL OF ETERNAL INFLATION AND THE TRANSITION FROM
CHANCE TO BIOLOGICAL EVOLUTION IN THE HISTORY OF LIFE.
"Origin of life is a chicken and egg problem: for biological evolution
that is governed, primarily, by natural selection, to take off,
efficient systems for replication and translation are required, but even barebones cores of these systems appear to be products of extensive selection."
"The currently favored (partial) solution is an RNA world without
proteins in which replication is catalyzed by ribozymes and which serves
as the cradle for the translation system. However, the RNA world faces
its own hard problems as ribozyme-catalyzed RNA replication remains a hypothesis and the selective pressures behind the origin of translation remain mysterious."
"The crucial question, then, is how was the minimal complexity attained
that is required to achieve the threshold replication fidelity. In even
the simplest modern systems, such as RNA viruses with the replication fidelity of only ~10-3, replication is catalyzed by a complex protein replicase; even disregarding accessory subunits present in most
replicases, the main catalytic subunit is a protein that consists of at least 300 amino acids. The replicase, of course, is produced by
translation of the respective mRNA which is mediated by a tremendously complex molecular machinery. Hence the first paradox of OORT: to attain
the minimal complexity required for a biological system to start on the
path of biological evolution, a system of a far greater complexity,
i.e., a highly evolved one, appears to be required. How such a system
could evolve, is a puzzle that defeats conventional evolutionary thinking."
"The second paradox of OORT pertains to the origin of the translation
system from within the RNA world via a Darwinian evolutionary process:
until the translation system produces functional proteins, there is no obvious selective advantage to the evolution of any parts of this
elaborate (even in its most primitive form) molecular machine."
"Despite considerable experimental and theoretical effort, no compelling scenarios currently exist for the origin of replication and translation,
the key processes that together comprise the core of biological systems
and the apparent pre-requisite of biological evolution. The RNA World concept might offer the best chance for the resolution of this conundrum
but so far cannot adequately account for the emergence of an efficient
RNA replicase or the translation system."
"The MWO version of the cosmological model of eternal inflation could suggest a way out of this conundrum because, in an infinite multiverse
with a finite number of distinct macroscopic histories (each repeated an infinite number of times), emergence of even highly complex systems by chance is not just possible but inevitable."
https://link.springer.com/article/10.1186/1745-6150-2-15
_______
"Whoa-hoh-oh, the gaps are gettin' bigger
-aYeah-eah, mmm they're gettin' bigger"
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