• Implantable 'cell factories'

    From JAB@here@is.invalid to sci.misc on Sun Mar 29 10:18:52 2026
    From Newsgroup: sci.misc

    Implantable 'cell factories' produce drugs inside the body

    Tiny devices containing cells engineered to continuously produce drugs
    could one day deliver medicines from inside the body without requiring
    patients to remember to administer doses.

    Researchers have designed a device called hybrid oxygenation
    bioelectronics system for implanted therapy, or HOBIT, in a step
    towards realising this goal.

    The system hides genetically-engineered cells from the immune system
    while producing its own oxygen and nutrients to keep the cells alive.

    In a proof-of-concept study the team engineered cells to produce an
    anti-HIV antibody, a GLP-1-like peptide used to treat type 2 diabetes
    and leptin, a hormone that regulates appetite and metabolism. They
    implanted the devices under the skin of rats and monitored drug levels
    in the animals' bloodstreams for 30 days.

    https://connectsci.au/news/news-parent/8108/Implantable-cell-factories-produce-drugs-inside

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