PART 6



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December 14, 1990

MIND7.ASC
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This file is a short description of a presentation given at the
1990 American ElectroEncephalographic Society Annual Meeting
We wish to thank "Sgt." Paul Carlson for providing this to KeelyNet.
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Study of the Frontal Speech Area with
TransCranial Magnetic Stimulation (TMS)
Department of Neurology, Univ. of Minnesota
and MINCEP, Minneapolis, MN 55455
research done by
Alvaro Pascual-Leone, Anil Dhuna and John R. Gates

TransCranial magnetic stimulation (TMS) at 8 to 25 Hertz was
performed on 4 subjects over the frontal area.

Over each side stimulation was performed with the 11 CM diameter
coil held flat on the scalp and the outer edge consecutively held
over the 16 positions of a 4 X 4 grid with 1.5 CM distance between
grid points. The anterior-inferior corner of the grid was electrode
position F7.

All subjects were being evaluated for surgical treatment of
medically intractable epilepsy. Intracarotid amytal test
demonstrated left hemisphere speed dominance in all.

TMS induced speech arrest in all patients when applied to a SINGLE
GRID POSITION over the LEFT HEMISPHERE.

In all subjects, this position WAS DIFFERENT and anterior to those
that induced laryngeal or contralateral face and hand movements.

This study demonstrates that TMS is capable of IDENTIFYING a frontal
area different from the motor cortex, which when stimulated INDUCES
SPEECH ARREST.

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Jerry W. Decker.........Ron Barker...........Chuck Henderson
Vangard Sciences/KeelyNet
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