From Newsgroup: talk.origins

To reiterate and focus previous discussion:

1. A human is a system of staggering functional complexity* (as are
many/all living things)

2. The claim that the human genome is 10% functional gives total genomic information to specify this system as only 80 megabytes:

3.2 billion base pairs x 10% x 2 / 8

Of course, nonlinear information translations, fractal formation of
capillary networks etc are involved in development from the zygote. Even allowing for this and other mechanisms, what amount of information is
needed to specify a human?

My argument is, the genome alone is nowhere near enough, from what we
know of the information needed to specify vastly simpler systems
designed by humans, even with the acknowledged difficulties in making comparisons.

Therefore, I propose that the ovum itself as a physico-chemical whole
must also be a major source of developmental information embedded in a three-dimensional distribution and structure of complex molecules
(cytoplasm, organelles, membrane; RNA, proteins, lipids, sugars).

My deduction is, the ovum contains a large amount of information for the development of a "generic" human (i.e. the subsystems listed below*);
the DNA also (presumably) contains information for the development of a generic human, as well as most/all the information for family traits.

This is not an argument from incredulity, rather, the burden of proof
rests with the claim that 80 MB in DNA is sufficient. Read the summary
below carefully, noting it is just that: a summary and tip of an iceberg
of a system of "deeply interdependent, multiscale biological
architecture, in which trillions of components are dynamically regulated
with molecular precision to maintain stability, adaptability".

If my contention is correct - to any degree - then this would obviously
have fundamental implications for the current theory of evolution, and
indeed our understanding of ourselves and life itself.

No denying that this appears to be a grandiose claim. Counterarguments welcome.

PS

If I understand correctly, the mainstream view of development does
consider genome + maternal provisioning + epigenetic state + physics + environment, with heredity dominated by DNA sequence. A key question
then is, does the egg carry substantial additional *heritable*
specification for the rCLgeneric" human that is not already accounted for
as a downstream product of the genome and known inheritance mechanisms?

_______


* The human body comprises 11 major physiological systems, each
exhibiting high functional complexity through scale, precision, and cross-system integration.

1. The *nervous system* provides rapid information processing, with ~86 billion neurons and ~10-|rU|rCo10-|rU| synapses enabling millisecond-scale control while consuming ~20% of resting metabolic energy. Humans possess ~2rCo3|u more cortical neurons than great apes, and this difference alone implies orders of magnitude greater combinatorial processing capacity,
given synaptic scaling; human prefrontal cortex expansion to ~25rCo30% of
the total cortex gives disproportionately dense long-range connections enabling abstract reasoning, symbolic thought, counterfactual planning,
and recursive language.

2. The *circulatory system* sustains organism-wide transport via
~100,000 km of blood vessels and a heart that beats ~100,000 times per
day, continuously distributing oxygen, nutrients, hormones, and immune
cells.

3. The *respiratory system* enables gas exchange through ~300 million
alveoli generating ~70 m-# of surface area, processing ~10,000 liters of
air per day.

4. The *digestive system* converts food into bioavailable energy along a
~9 m tract, with ~30rCo40 trillion gut microbes and ~30rCo40 m-# of
absorptive surface area in the small intestine.

5. The *endocrine system* coordinates long-range regulation using
hormones effective at picomolarrConanomolar concentrations, exerting organism-wide control through nested feedback loops.

6. The *immune system* provides adaptive defense with ~10-|-|rCo10-|-# active immune cells and the capacity to generate >10-|-# distinct antibody
variants with long-term memory.

7. The *musculoskeletal system* enables movement and structural support through ~206 bones and ~600 muscles, with continuous mechanical loading
and bone remodeling (~5rCo10% annually).

8. The *integumentary system* forms a multifunctional protective
interface covering ~1.5rCo2.0 m-# and containing ~20 billion cells, integrating mechanical protection, sensation, and immune signaling.

9. The *urinary (renal) system* maintains chemical homeostasis by
filtering ~180 liters of blood per day across ~2 million nephrons,
reabsorbing >99% of filtrate with high selectivity.

10. The *reproductive system* supports species continuity through
hormonally regulated gamete production (up to hundreds of millions of
sperm per day in males) and cyclic reproductive physiology in females.

11. The *lymphatic system* complements circulation and immunity by
returning ~2rCo4 liters of interstitial fluid daily and coordinating
immune surveillance across hundreds of lymph nodes.

Taken together, these systems form a deeply interdependent, multiscale biological architecture, in which trillions of components are
dynamically regulated with molecular precision to maintain stability, adaptability, and continuity of the human organism.

(Summary by ChatGPT 5.2)

--- Synchronet 3.21a-Linux NewsLink 1.2

From Newsgroup: talk.origins

On 30/12/2025 2:54 pm, MarkE wrote:

To reiterate and focus previous discussion:

1. A human is a system of staggering functional complexity* (as are
many/all living things)

2. The claim that the human genome is 10% functional gives total genomic information to specify this system as only 80 megabytes:

-a-a-a 3.2 billion base pairs x 10% x 2 / 8

Of course, nonlinear information translations, fractal formation of capillary networks etc are involved in development from the zygote. Even allowing for this and other mechanisms, what amount of information is
needed to specify a human?

My argument is, the genome alone is nowhere near enough, from what we
know of the information needed to specify vastly simpler systems
designed by humans, even with the acknowledged difficulties in making comparisons.

Therefore, I propose that the ovum itself as a physico-chemical whole
must also be a major source of developmental information embedded in a three-dimensional distribution and structure of complex molecules (cytoplasm, organelles, membrane; RNA, proteins, lipids, sugars).

My deduction is, the ovum contains a large amount of information for the development of a "generic" human (i.e. the subsystems listed below*);
the DNA also (presumably) contains information for the development of a generic human, as well as most/all the information for family traits.

This is not an argument from incredulity, rather, the burden of proof
rests with the claim that 80 MB in DNA is sufficient. Read the summary
below carefully, noting it is just that: a summary and tip of an iceberg
of a system of "deeply interdependent, multiscale biological
architecture, in which trillions of components are dynamically regulated with molecular precision to maintain stability, adaptability".

If my contention is correct - to any degree - then this would obviously
have fundamental implications for the current theory of evolution, and indeed our understanding of ourselves and life itself.

No denying that this appears to be a grandiose claim. Counterarguments welcome.

As I've mentioned before, what I'm suggesting accords with Dennis
Noble's perspective (e.g. https://youtu.be/aELkemLP6XQ?si=Jv6axjFbR98m33uv)

Also, Philip Ball's book "How Life Works: A UserrCOs Guide to the New Biology", which proposes a shift away from genetic reductionism, and
assess that the literature has already passed "peak gene".

Don't be alarmed - Ball nonetheless asserts his evolutionist
credentials: "I believe we are at the beginning of a profound rethinking
of how life works. Far from being some new paradigm that threatens
Darwinism (or more generally, evolutionary theory), it is a rather
glorious extension of it . Frankly, I think we have underestimated
evolution."

PS

If I understand correctly, the mainstream view of development does
consider genome + maternal provisioning + epigenetic state + physics + environment, with heredity dominated by DNA sequence. A key question
then is, does the egg carry substantial additional *heritable*
specification for the rCLgeneric" human that is not already accounted for
as a downstream product of the genome and known inheritance mechanisms?

_______

* The human body comprises 11 major physiological systems, each
exhibiting high functional complexity through scale, precision, and cross-system integration.

1. The *nervous system* provides rapid information processing, with ~86 billion neurons and ~10-|rU|rCo10-|rU| synapses enabling millisecond-scale control while consuming ~20% of resting metabolic energy. Humans possess ~2rCo3|u more cortical neurons than great apes, and this difference alone implies orders of magnitude greater combinatorial processing capacity,
given synaptic scaling; human prefrontal cortex expansion to ~25rCo30% of the total cortex gives disproportionately dense long-range connections enabling abstract reasoning, symbolic thought, counterfactual planning,
and recursive language.

2. The *circulatory system* sustains organism-wide transport via
~100,000 km of blood vessels and a heart that beats ~100,000 times per
day, continuously distributing oxygen, nutrients, hormones, and immune cells.

3. The *respiratory system* enables gas exchange through ~300 million alveoli generating ~70 m-# of surface area, processing ~10,000 liters of
air per day.

4. The *digestive system* converts food into bioavailable energy along a
~9 m tract, with ~30rCo40 trillion gut microbes and ~30rCo40 m-# of absorptive surface area in the small intestine.

5. The *endocrine system* coordinates long-range regulation using
hormones effective at picomolarrConanomolar concentrations, exerting organism-wide control through nested feedback loops.

6. The *immune system* provides adaptive defense with ~10-|-|rCo10-|-# active
immune cells and the capacity to generate >10-|-# distinct antibody
variants with long-term memory.

7. The *musculoskeletal system* enables movement and structural support through ~206 bones and ~600 muscles, with continuous mechanical loading
and bone remodeling (~5rCo10% annually).

8. The *integumentary system* forms a multifunctional protective
interface covering ~1.5rCo2.0 m-# and containing ~20 billion cells, integrating mechanical protection, sensation, and immune signaling.

9. The *urinary (renal) system* maintains chemical homeostasis by
filtering ~180 liters of blood per day across ~2 million nephrons, reabsorbing >99% of filtrate with high selectivity.

10. The *reproductive system* supports species continuity through
hormonally regulated gamete production (up to hundreds of millions of
sperm per day in males) and cyclic reproductive physiology in females.

11. The *lymphatic system* complements circulation and immunity by
returning ~2rCo4 liters of interstitial fluid daily and coordinating
immune surveillance across hundreds of lymph nodes.

Taken together, these systems form a deeply interdependent, multiscale biological architecture, in which trillions of components are
dynamically regulated with molecular precision to maintain stability, adaptability, and continuity of the human organism.

(Summary by ChatGPT 5.2)

A

--- Synchronet 3.21a-Linux NewsLink 1.2

From Newsgroup: talk.origins

On 12/29/2025 9:54 PM, MarkE wrote:

To reiterate and focus previous discussion:

1. A human is a system of staggering functional complexity* (as are
many/all living things)

2. The claim that the human genome is 10% functional gives total genomic information to specify this system as only 80 megabytes:

-a-a-a 3.2 billion base pairs x 10% x 2 / 8

Of course, nonlinear information translations, fractal formation of capillary networks etc are involved in development from the zygote. Even allowing for this and other mechanisms, what amount of information is
needed to specify a human?

My argument is, the genome alone is nowhere near enough, from what we
know of the information needed to specify vastly simpler systems
designed by humans, even with the acknowledged difficulties in making comparisons.

Therefore, I propose that the ovum itself as a physico-chemical whole
must also be a major source of developmental information embedded in a three-dimensional distribution and structure of complex molecules (cytoplasm, organelles, membrane; RNA, proteins, lipids, sugars).

That the egg cell is required for reproduction has been understood for a couple of centuries. A functioning cell has been known to be required
to develop a functioning organism for a very long time. Just putting
DNA into a lipid bubble will not result in a functioning cell and my
guess is that it has never seriously been considered to be possible.
Even the artificial genome developers have to put their genome into a bacterium that they have removed the DNA out of.

You do not seem to understand how descent with modification, biological evolution, works. New genetic variants and new combinations of genetic variants inherited through sexual reproduction all have to work within
what is already working to create the organism from a fertilized egg
cell. It is the way that reproduction has worked since the first cells evolved a means to make sure an adequate set of genes was transferred
into each daughter cell of mitotic cell division.

Every genetic change has to be able to develop a human being from that
single fertilized egg cell or it is not propagated in the population.
This has been going on for billions of years. Every change has to work
within what is already working. That is how biological evolution works.
Eukaryotes evolved sex and gamete production over a billion years ago
as single celled organisms, and the human egg cell is the result of over
a billion years of change. Every change had to work within what was
already working.

Ron Okimoto

My deduction is, the ovum contains a large amount of information for the development of a "generic" human (i.e. the subsystems listed below*);
the DNA also (presumably) contains information for the development of a generic human, as well as most/all the information for family traits.

This is not an argument from incredulity, rather, the burden of proof
rests with the claim that 80 MB in DNA is sufficient. Read the summary
below carefully, noting it is just that: a summary and tip of an iceberg
of a system of "deeply interdependent, multiscale biological
architecture, in which trillions of components are dynamically regulated with molecular precision to maintain stability, adaptability".

If my contention is correct - to any degree - then this would obviously
have fundamental implications for the current theory of evolution, and indeed our understanding of ourselves and life itself.

No denying that this appears to be a grandiose claim. Counterarguments welcome.

PS

If I understand correctly, the mainstream view of development does
consider genome + maternal provisioning + epigenetic state + physics + environment, with heredity dominated by DNA sequence. A key question
then is, does the egg carry substantial additional *heritable*
specification for the rCLgeneric" human that is not already accounted for
as a downstream product of the genome and known inheritance mechanisms?

_______

* The human body comprises 11 major physiological systems, each
exhibiting high functional complexity through scale, precision, and cross-system integration.

1. The *nervous system* provides rapid information processing, with ~86 billion neurons and ~10-|rU|rCo10-|rU| synapses enabling millisecond-scale control while consuming ~20% of resting metabolic energy. Humans possess ~2rCo3|u more cortical neurons than great apes, and this difference alone implies orders of magnitude greater combinatorial processing capacity,
given synaptic scaling; human prefrontal cortex expansion to ~25rCo30% of the total cortex gives disproportionately dense long-range connections enabling abstract reasoning, symbolic thought, counterfactual planning,
and recursive language.

2. The *circulatory system* sustains organism-wide transport via
~100,000 km of blood vessels and a heart that beats ~100,000 times per
day, continuously distributing oxygen, nutrients, hormones, and immune cells.

3. The *respiratory system* enables gas exchange through ~300 million alveoli generating ~70 m-# of surface area, processing ~10,000 liters of
air per day.

4. The *digestive system* converts food into bioavailable energy along a
~9 m tract, with ~30rCo40 trillion gut microbes and ~30rCo40 m-# of absorptive surface area in the small intestine.

5. The *endocrine system* coordinates long-range regulation using
hormones effective at picomolarrConanomolar concentrations, exerting organism-wide control through nested feedback loops.

6. The *immune system* provides adaptive defense with ~10-|-|rCo10-|-# active
immune cells and the capacity to generate >10-|-# distinct antibody
variants with long-term memory.

7. The *musculoskeletal system* enables movement and structural support through ~206 bones and ~600 muscles, with continuous mechanical loading
and bone remodeling (~5rCo10% annually).

8. The *integumentary system* forms a multifunctional protective
interface covering ~1.5rCo2.0 m-# and containing ~20 billion cells, integrating mechanical protection, sensation, and immune signaling.

9. The *urinary (renal) system* maintains chemical homeostasis by
filtering ~180 liters of blood per day across ~2 million nephrons, reabsorbing >99% of filtrate with high selectivity.

10. The *reproductive system* supports species continuity through
hormonally regulated gamete production (up to hundreds of millions of
sperm per day in males) and cyclic reproductive physiology in females.

11. The *lymphatic system* complements circulation and immunity by
returning ~2rCo4 liters of interstitial fluid daily and coordinating
immune surveillance across hundreds of lymph nodes.

Taken together, these systems form a deeply interdependent, multiscale biological architecture, in which trillions of components are
dynamically regulated with molecular precision to maintain stability, adaptability, and continuity of the human organism.

(Summary by ChatGPT 5.2)

--- Synchronet 3.21a-Linux NewsLink 1.2

From Newsgroup: talk.origins

On 30/12/2025 03:54, MarkE wrote:

To reiterate and focus previous discussion:

1. A human is a system of staggering functional complexity* (as are
many/all living things)

2. The claim that the human genome is 10% functional gives total genomic information to specify this system as only 80 megabytes:

-a-a-a 3.2 billion base pairs x 10% x 2 / 8

Of course, nonlinear information translations, fractal formation of capillary networks etc are involved in development from the zygote. Even allowing for this and other mechanisms, what amount of information is
needed to specify a human?

My argument is, the genome alone is nowhere near enough, from what we
know of the information needed to specify vastly simpler systems
designed by humans, even with the acknowledged difficulties in making comparisons.

Therefore, I propose that the ovum itself as a physico-chemical whole
must also be a major source of developmental information embedded in a three-dimensional distribution and structure of complex molecules (cytoplasm, organelles, membrane; RNA, proteins, lipids, sugars).

My deduction is, the ovum contains a large amount of information for the development of a "generic" human (i.e. the subsystems listed below*);
the DNA also (presumably) contains information for the development of a generic human, as well as most/all the information for family traits.

This is not an argument from incredulity, rather, the burden of proof
rests with the claim that 80 MB in DNA is sufficient. Read the summary
below carefully, noting it is just that: a summary and tip of an iceberg
of a system of "deeply interdependent, multiscale biological
architecture, in which trillions of components are dynamically regulated with molecular precision to maintain stability, adaptability".

If my contention is correct - to any degree - then this would obviously
have fundamental implications for the current theory of evolution, and indeed our understanding of ourselves and life itself.

No denying that this appears to be a grandiose claim. Counterarguments welcome.

PS

If I understand correctly, the mainstream view of development does
consider genome + maternal provisioning + epigenetic state + physics + environment, with heredity dominated by DNA sequence. A key question
then is, does the egg carry substantial additional *heritable*
specification for the rCLgeneric" human that is not already accounted for
as a downstream product of the genome and known inheritance mechanisms?

_______

* The human body comprises 11 major physiological systems, each
exhibiting high functional complexity through scale, precision, and cross-system integration.

1. The *nervous system* provides rapid information processing, with ~86 billion neurons and ~10-|rU|rCo10-|rU| synapses enabling millisecond-scale control while consuming ~20% of resting metabolic energy. Humans possess ~2rCo3|u more cortical neurons than great apes, and this difference alone implies orders of magnitude greater combinatorial processing capacity,
given synaptic scaling; human prefrontal cortex expansion to ~25rCo30% of the total cortex gives disproportionately dense long-range connections enabling abstract reasoning, symbolic thought, counterfactual planning,
and recursive language.

2. The *circulatory system* sustains organism-wide transport via
~100,000 km of blood vessels and a heart that beats ~100,000 times per
day, continuously distributing oxygen, nutrients, hormones, and immune cells.

3. The *respiratory system* enables gas exchange through ~300 million alveoli generating ~70 m-# of surface area, processing ~10,000 liters of
air per day.

4. The *digestive system* converts food into bioavailable energy along a
~9 m tract, with ~30rCo40 trillion gut microbes and ~30rCo40 m-# of absorptive surface area in the small intestine.

5. The *endocrine system* coordinates long-range regulation using
hormones effective at picomolarrConanomolar concentrations, exerting organism-wide control through nested feedback loops.

6. The *immune system* provides adaptive defense with ~10-|-|rCo10-|-# active
immune cells and the capacity to generate >10-|-# distinct antibody
variants with long-term memory.

7. The *musculoskeletal system* enables movement and structural support through ~206 bones and ~600 muscles, with continuous mechanical loading
and bone remodeling (~5rCo10% annually).

8. The *integumentary system* forms a multifunctional protective
interface covering ~1.5rCo2.0 m-# and containing ~20 billion cells, integrating mechanical protection, sensation, and immune signaling.

9. The *urinary (renal) system* maintains chemical homeostasis by
filtering ~180 liters of blood per day across ~2 million nephrons, reabsorbing >99% of filtrate with high selectivity.

10. The *reproductive system* supports species continuity through
hormonally regulated gamete production (up to hundreds of millions of
sperm per day in males) and cyclic reproductive physiology in females.

11. The *lymphatic system* complements circulation and immunity by
returning ~2rCo4 liters of interstitial fluid daily and coordinating
immune surveillance across hundreds of lymph nodes.

Taken together, these systems form a deeply interdependent, multiscale biological architecture, in which trillions of components are
dynamically regulated with molecular precision to maintain stability, adaptability, and continuity of the human organism.

(Summary by ChatGPT 5.2)

The right isoceles triangle, the sqrt(2):1 rectangle, the
Harter-Heighway dragon, the twindragon, the tame twindragon, and the
Levy Curve, are all geometrical objects which can be dissected into themselves.

The right isoceles triangle and sqrt(2):1 rectangle have non-fractal, non-self-intersecting, boundaries.

The sqrt(2):1 rectangle tiles the plane with one copy in the minimal
unit cell.

The right isoceles triangle tiles the plane with two copies in the
minimal unit cell.

The remainder have fractal boundaries, so you're already at greater
complexity than the human body. (Bits of the human body are self-similar
only over a range of scales, instead of over all scales.)

The twindragon and tame twindragon have non-self intersecting
boundaries, and tile the plane with one copy in the minimal unit cell.

The Harter-Heighway Dragon has a self-intersecting boundary, but no
holes, consisting of an infinite number of filled areas, each connected
to two others at single points. It tiles the plane with two copies in
the minimal unit cell.

The Levy Curve has a self-intersecting boundary, and an infinite number
of holes. (It's hard to spot any filled area on a small scale image.) It
tiles the plane with four copies in the minimal unit cell.

These 6 geometrical figures show a vast difference in the amount of information needed for a "blueprint". However each one be specified by
just 8 numbers and a mathematical definition of what the numbers represent.

Algorithmic and structural complexity (corresponding to Kolmogorov and
Shannon information) can be very different. What's relevant here is algorithmic complexity, not structural complexity. The human brain might
have several times the structural complexity of the chimpanzee brain,
and the elephant brain several times the structural complexity of the
elephant brain, but the differences in algorithmic complexity are much smaller.

Ask yourself what qualitative (rather than quantitative) differences
there are between human and chimpanzee anatomy?
--
alias Ernest Major

--- Synchronet 3.21a-Linux NewsLink 1.2

From Newsgroup: talk.origins

On 31/12/2025 9:38 am, Ernest Major wrote:

On 30/12/2025 03:54, MarkE wrote:

To reiterate and focus previous discussion:

1. A human is a system of staggering functional complexity* (as are
many/all living things)

2. The claim that the human genome is 10% functional gives total
genomic information to specify this system as only 80 megabytes:

-a-a-a-a 3.2 billion base pairs x 10% x 2 / 8

Of course, nonlinear information translations, fractal formation of
capillary networks etc are involved in development from the zygote.
Even allowing for this and other mechanisms, what amount of
information is needed to specify a human?

My argument is, the genome alone is nowhere near enough, from what we
know of the information needed to specify vastly simpler systems
designed by humans, even with the acknowledged difficulties in making
comparisons.

Therefore, I propose that the ovum itself as a physico-chemical whole
must also be a major source of developmental information embedded in a
three-dimensional distribution and structure of complex molecules
(cytoplasm, organelles, membrane; RNA, proteins, lipids, sugars).

My deduction is, the ovum contains a large amount of information for
the development of a "generic" human (i.e. the subsystems listed
below*); the DNA also (presumably) contains information for the
development of a generic human, as well as most/all the information
for family traits.

This is not an argument from incredulity, rather, the burden of proof
rests with the claim that 80 MB in DNA is sufficient. Read the summary
below carefully, noting it is just that: a summary and tip of an
iceberg of a system of "deeply interdependent, multiscale biological
architecture, in which trillions of components are dynamically
regulated with molecular precision to maintain stability, adaptability".

If my contention is correct - to any degree - then this would
obviously have fundamental implications for the current theory of
evolution, and indeed our understanding of ourselves and life itself.

No denying that this appears to be a grandiose claim. Counterarguments
welcome.

PS

If I understand correctly, the mainstream view of development does
consider genome + maternal provisioning + epigenetic state + physics +
environment, with heredity dominated by DNA sequence. A key question
then is, does the egg carry substantial additional *heritable*
specification for the rCLgeneric" human that is not already accounted
for as a downstream product of the genome and known inheritance
mechanisms?

_______


* The human body comprises 11 major physiological systems, each
exhibiting high functional complexity through scale, precision, and
cross-system integration.

1. The *nervous system* provides rapid information processing, with
~86 billion neurons and ~10-|rU|rCo10-|rU| synapses enabling millisecond-scale
control while consuming ~20% of resting metabolic energy. Humans
possess ~2rCo3|u more cortical neurons than great apes, and this
difference alone implies orders of magnitude greater combinatorial
processing capacity, given synaptic scaling; human prefrontal cortex
expansion to ~25rCo30% of the total cortex gives disproportionately
dense long-range connections enabling abstract reasoning, symbolic
thought, counterfactual planning, and recursive language.

2. The *circulatory system* sustains organism-wide transport via
~100,000 km of blood vessels and a heart that beats ~100,000 times per
day, continuously distributing oxygen, nutrients, hormones, and immune
cells.

3. The *respiratory system* enables gas exchange through ~300 million
alveoli generating ~70 m-# of surface area, processing ~10,000 liters
of air per day.

4. The *digestive system* converts food into bioavailable energy along
a ~9 m tract, with ~30rCo40 trillion gut microbes and ~30rCo40 m-# of
absorptive surface area in the small intestine.

5. The *endocrine system* coordinates long-range regulation using
hormones effective at picomolarrConanomolar concentrations, exerting
organism-wide control through nested feedback loops.

6. The *immune system* provides adaptive defense with ~10-|-|rCo10-|-#
active immune cells and the capacity to generate >10-|-# distinct
antibody variants with long-term memory.

7. The *musculoskeletal system* enables movement and structural
support through ~206 bones and ~600 muscles, with continuous
mechanical loading and bone remodeling (~5rCo10% annually).

8. The *integumentary system* forms a multifunctional protective
interface covering ~1.5rCo2.0 m-# and containing ~20 billion cells,
integrating mechanical protection, sensation, and immune signaling.

9. The *urinary (renal) system* maintains chemical homeostasis by
filtering ~180 liters of blood per day across ~2 million nephrons,
reabsorbing >99% of filtrate with high selectivity.

10. The *reproductive system* supports species continuity through
hormonally regulated gamete production (up to hundreds of millions of
sperm per day in males) and cyclic reproductive physiology in females.

11. The *lymphatic system* complements circulation and immunity by
returning ~2rCo4 liters of interstitial fluid daily and coordinating
immune surveillance across hundreds of lymph nodes.

Taken together, these systems form a deeply interdependent, multiscale
biological architecture, in which trillions of components are
dynamically regulated with molecular precision to maintain stability,
adaptability, and continuity of the human organism.

(Summary by ChatGPT 5.2)

The right isoceles triangle, the sqrt(2):1 rectangle, the Harter-
Heighway dragon, the twindragon, the tame twindragon, and the Levy
Curve, are all geometrical objects which can be dissected into themselves.

The right isoceles triangle and sqrt(2):1 rectangle have non-fractal, non-self-intersecting, boundaries.

The sqrt(2):1 rectangle tiles the plane with one copy in the minimal
unit cell.

The right isoceles triangle tiles the plane with two copies in the
minimal unit cell.

The remainder have fractal boundaries, so you're already at greater complexity than the human body. (Bits of the human body are self-similar only over a range of scales, instead of over all scales.)

The twindragon and tame twindragon have non-self intersecting
boundaries, and tile the plane with one copy in the minimal unit cell.

The Harter-Heighway Dragon has a self-intersecting boundary, but no
holes, consisting of an infinite number of filled areas, each connected
to two others at single points. It tiles the plane with two copies in
the minimal unit cell.

The Levy Curve has a self-intersecting boundary, and an infinite number
of holes. (It's hard to spot any filled area on a small scale image.) It tiles the plane with four copies in the minimal unit cell.

These 6 geometrical figures show a vast difference in the amount of information needed for a "blueprint". However each one be specified by
just 8 numbers and a mathematical definition of what the numbers represent.

Algorithmic and structural complexity (corresponding to Kolmogorov and Shannon information) can be very different. What's relevant here is algorithmic complexity, not structural complexity. The human brain might have several times the structural complexity of the chimpanzee brain,
and the elephant brain several times the structural complexity of the elephant brain, but the differences in algorithmic complexity are much smaller.

Ask yourself what qualitative (rather than quantitative) differences
there are between human and chimpanzee anatomy?

Sure, we've all written a program to implement the logistic equation in
its simplicity to produce what appears to be the endless (and beautiful) complexity of Mandelbrot and Julia sets.

And yes, fractals certainly provide an efficient means of expressing
certain structures, which is why I said, "Of course, nonlinear
information translations, fractal formation of capillary networks etc
are involved in development from the zygote."

But spectacular as these are, they are not able to represent the breadth
and depth functional complexity that living things are saturated in: the
11 systems listed "form a deeply interdependent, multiscale biological architecture, in which trillions of components are dynamically regulated
with molecular precision to maintain stability, adaptability, and
continuity of the human organism."

Do you think 80MB, exploiting fractals, is sufficient to specify the development and integrated functioning of a human as described?









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