• Complex genetics of Amorphochlora amoebiformis

    From RonO@rokimoto557@gmail.com to talk-origins on Sun Dec 21 12:21:58 2025
    From Newsgroup: talk.origins

    https://phys.org/news/2025-12-discovery-intron-rich-eukaryotic-genome.html

    https://academic.oup.com/dnaresearch/advance-article/doi/10.1093/dnares/dsaf035/8348290

    This organism is touted as a eukaryote with the most intron rich genome.
    It's nuclear genome is 214 million base pairs with 17,500 protein
    genes, but introns in those genes account for 74% of the genomic
    sequence. It's coding sequence is packed with noncoding exons. They
    claim that these are spliceosomal introns and not self splicing
    transposable parasitic introns. So this lineage went nuts in when it
    came to introducing introns into coding sequence. For humans more than
    half of the 3 billion base-pair genome is made up of repetitive sequence
    or transposable elements that can still be identified as being
    transposons. Most of the rest is likely old transposon sequence that
    has degenerated past recognition. Less than 2% of the human genome is
    coding sequence (exons) and introns within those genes account for
    around 25% of the genome. Introns can be composed of a lot of different sequence origins like basically random sequence, transposons or
    pseudogene insertions. There are even other coding genes contained
    within some of the larger introns. My guess is that this critter's
    introns are just as complex.

    Amoebiformis has 4 genomes (1 nuclear and 3 organellar genomes). One of
    it's organellar genomes is derived from a eukaryotic algae and the other
    two are of bacterial origin. For some reason it is transferring
    mitochondrial sequence to it's nuclear genome, but has not done that for
    the plastid genomes.

    This is a strange little beasty.

    Ron Okimoto

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