From Newsgroup: rec.sport.rowing

<div>After attending a lecture at a conference on the drug L-DOPA and its success for patients with Parkinson's disease, Sayer believes the drug may offer a breakthrough for his own group of patients. A trial run with Leonard yields astounding results: Leonard completely "awakens" from his catatonic state. This success inspires Sayer to ask for funding from donors so that all the catatonic patients can receive the L-DOPA medication and gain "awakenings" to reality and the present.</div><div></div><div></div><div></div><div></div><div></div><div>The Awakening 1080p Full Movie</div><div></div><div>Download Zip: https://t.co/UAecd1xx7Z </div><div></div><div></div><div>Although Sayer and the hospital staff are thrilled by the success of L-DOPA with this group of patients, they soon learn that it is a temporary result. As the first to "awaken", Leonard is also the first to demonstrate the limited duration of this period of "awakening". Leonard's tics grow more and more prominent, and he starts to shuffle more as he walks. All of the patients are forced to witness what will eventually happen to them. He soon begins to have full body spasms and can hardly move. Leonard puts up well with the pain, and asks Sayer to film him, in hopes that he would someday contribute to research that may eventually help others. Leonard acknowledges what is happening to him and has a last lunch with Paula, where he tells her he cannot see her anymore. When he is about to leave, Paula dances with him. For this short period of time, his spasms disappear. Leonard and Sayer reconcile their differences, but Leonard returns to his catatonic state soon after. The other patients' fears are similarly realized as each eventually returns to catatonia, no matter how much their L-DOPA dosages are increased.</div><div></div><div></div><div>Awakening is a crucial event for the organism. The transition from sleep to waking implies physiological processes which lead to a new behavioural state. Spontaneous awakenings have varying features which may change as a function of several factors. The latter include intrasleep architecture, circadian phase, time awake, age, or disordered sleep. Despite its clear theoretical and clinical importance, the topic of awakening (in humans) has received little attention so far. This contribution focuses on major issues which relate to awakening from both basic (experimental) and clinical research. Recent knowledge on neurophysiological mechanisms is reported. The experimental data which provide in the human suggestions on the regulation of awakening are discussed, mainly those concerning sleep architecture and homeostatic/circadian factors also in a life-span perspective, since age is a powerful factor which may influence awakening. Clinical contributions will examine two main sleep disorders: insomnia and hypersomnia. Daytime functioning is shown in insomniac patients and compared to other pathologies like sleep apnea. A final section evokes links between some types of night waking and psychological factors.</div><div></div><div></div><div>A paper published in Nature in April raised the intriguing possibility that optical therapies might be developed to treat neurological disorders. That work, in tissue slices and in C. elegans roundworms, showed that brain cells can be genetically engineered to alter their activity in response to pulses of different colours of light. A follow-up study now shows that behaviour can be modified in a living mammal by similar means. Hypocretin (Hcrt)-producing neurons in the hypothalamus are active during transitions from sleep to waking states. Optical stimulation of mouse Hcrt neurons engineered to respond to light increases the likelihood of transition from sleep to wakefulness, with higher frequencies causing more abrupt awakening. As Hcrt deficiency is linked to narcolepsy, these results may provide insights into sleep disorders.</div><div></div><div></div><div></div><div></div><div></div><div> dd2b598166</div>
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