• How does insulin resistance develop, and what are its early sign?

    From Mike Dippel@999:1/1 to All on Tue Jun 3 10:03:18 2025
    Insulin resistance develops when the body's cells become less responsive to insulin, the
    hormone that regulates blood sugar.

    This leads to elevated blood sugar levels. Early signs may be subtle or absent, but can
    include fatigue, increased hunger, darkened skin patches (acanthosis nigricans), and
    weight gain, particularly around the waist.

    When your body is exposed to too much blood sugar over an extended period of time,
    you can develop insulin resistance.

    Here's what that means: A lot of blood sugar enters your bloodstream. Your pancreas
    pumps out high levels of insulin to get more blood sugar into your cells.

    The two main factors that seem to contribute to insulin resistance are excess body fat,
    especially around your belly, and a lack of physical activity.

    Having a family history of insulin resistance (family members with prediabetes, type 2
    diabetes, and/or PCOS) can also contribute to insulin resistance.

    Follow this thread at: https://expressyourexperience.quora.com/How-does-insulin-resistance-develop-and-
    what-are-its-early-sign

    Mike Dippel

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