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https://www.nature.com/articles/d41586-025-02635-2
For some three billion years, unicellular
organisms ruled Earth. Then, around one billion
years ago, a new chapter of life began. Early
attempts at team living began to stick, paving the
way for the evolution of complex organisms,
including animals, plants and fungi.
Across all known life, the move to
multicellularity happened at least 40 times,
suggests one study. But, in animals, it seems
to have occurred only once.
Beginning in the early 2000s, researchers
interested in this remarkable event made a
series of unexpected discoveries. The prevailing
view held that a flood of genes had to evolve to
enable the key properties of multicellularity:
the ability of cells to stick together,
communication using molecular signals and the
coordinated regulation of gene expression that
causes each cell to specialize and take its
position in the organism. But studies found that
some unicellular organisms express a slew of
proteins that control key properties of
multicellularity in animals. The molecular
toolkit required for multicellularity seems to
have existed well before the first animals came
to be.
...